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手持一堆垃圾
2021-02-10
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2021-02-08
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Platform),以及全球首个融合了精准计算设计与实验构造并集酵母和噬菌体于一体的高通量筛选平台。</p>\n<p>多样性动态精准抗体库是天演药业的核心技术专利。该DPL平台由计算物理技术与AI和大数据相结合提供支持,可对由海量抗体氨基酸序列产生的潜在无限数量的动态结合界面结构进行采样,生产同时具备优异生物学功能与成药性的先到抗体,从而大幅提高抗体药物发现的效率。</p>\n<p>基于这一自有专利平台,天演药物现开发了三个核心产品:ADG106、ADG116和ADG126。其中用于治疗晚期实体瘤、非霍奇金淋巴瘤或NHL的ADG106正在中美两国进行临床试验,已被数据观察到具有良好的抗肿瘤活性与耐受性,最有望实现商业化。</p>\n<p>天演药业的另一产品ADG126,旨在解决与现有批准的CTLA-4免疫肿瘤疗法的MOA相关的毒性和功效问题,并扩大CTLA-4作为癌症治疗靶标的潜力。该产品现已由FDA获批,将于今年在美开展Ⅰ期临床试验。</p>\n<p>作为生物抗体领域的新星企业的创始人,天演药业创始人罗培志在医药科技领域颇为成功。罗培志毕业于北京大学,在美国芝加哥大学获得博士学位。2000年,罗培志创立了一家名为Abmaxis的生物医药公司,开创了不依赖抗体抗原的三维实验结构,可以设计和优化抗体的计算及筛选方法,为全球多家生物公司的创新药开发提供技术服务。因其技术创新,Abmaxis在2006年被默沙东收购,罗培志本人也受聘到默沙东担任全球生物制药研发主任。</p>\n<p>2011年左右,罗培志在校友、药明康德创始人李革的影响下,决定回国创业,很快将公司落户在离与药明康德总部无锡不远的苏州。2014年,天演药业完成A轮融资,共募集资金800万美元。领投机构包括药康明德创投基金、富达(波士顿)生物科技基金等。2016年天演药业的B轮融资,药明康德继续跟投,帮助天演药业再度融资2800万美元。此后的两年中,天演药业陆续完成了C轮、D轮融资,背后都有药明康德的身影。</p>\n<p>截至目前,药明康德仍以全资子公司无锡市医药科技保险基金的身份持有天演药业10.8%的股份。</p>\n<p>在国内CRO赛道上,药明康德无疑是领跑者。从2012年起,药明康德就开始布局投资具有潜力的Biotech公司,前期投资入股,获取未来收益。药明康德本身便具有一定的临床试验服务和生物分析等能力,在资金之外,其也可以凭借这些服务为初创公司提供支持。比如天演药业,在2018年至2020年两年里,共向药明康德购买了近1500万美元的研发服务与质量检测服务。</p>\n<p>财报显示,2018年、2019年及截至2020年9月30日的前9个月,由于产品均未上市,公司收入完全来自向制药公司新基授权专利所得,分别为151.1万美元、48万美元及31万美元。同一时期,研发支出在逐年上升,分别为1608.1万美元、1621.2万美元和2356.8万美元。</p>\n<p>没有能产生大额收入的上市药物,持续不断的研发投入也造成天演药业同期净亏损分别为1430.3万美元、1667.8万美元、2981.5万美元,归属于普通股股东的基本和摊薄每股亏损分别为0.94美元、1.10美元和1.89美元。</p>\n<p>目前,天演药业也在加大科研上的投入。公司在招股书中介绍,天演药业打算利用此次发行的净收益95%用于推进候选药物的试验,其中约26%的资金用于ADG106第一阶段试验和第二阶段试验的进展;26%的资金用于ADG126和ADG116;43%用于公司的技术和平台开发以及临床前候选药物的开发;剩余约5%用于营运资金和其他一般公司用途。</p>","collect":0,"html":"<!DOCTYPE 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}\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n天演药业今日挂牌纳斯达克,开盘涨近9%\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time\">2021-02-10 00:54</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>2月9日,临床阶段生物药企<a href=\"https://laohu8.com/S/ADAG\">天演药业</a>正式在纳斯达克挂牌上市,开盘涨8.95%,报20.7美元,市值8.73亿美元。</p>\n<p><img src=\"https://static.tigerbbs.com/62e01ad7e249639d98c7aa993a51a167\" tg-width=\"1340\" tg-height=\"833\"></p>\n<p>天演药业发行价为19美元位于价格指导区间顶端,据悉本次发行735.4万份ADS,市值达到8.01亿美元。高盛、摩根士丹利、Jeffery为联席主承销商,华兴资本为副承销商。</p>\n<p>根据媒体报道,天演药业与CRO巨头药明康德的关系密切,药明康德系天演药业投资方之一,股份占比10.8%。有分析称,天演药业赴美上市,幕后助力者正是药明康德。</p>\n<p>根据官方信息,天演药业成立于2011年,致力于改变基于抗体的新型癌症免疫疗法的发现和开发。成立后的几年间,天演药业自主开发了动态精准抗体技术,建立起全球最大的多样性动态精准抗体库(DPL Platform),以及全球首个融合了精准计算设计与实验构造并集酵母和噬菌体于一体的高通量筛选平台。</p>\n<p>多样性动态精准抗体库是天演药业的核心技术专利。该DPL平台由计算物理技术与AI和大数据相结合提供支持,可对由海量抗体氨基酸序列产生的潜在无限数量的动态结合界面结构进行采样,生产同时具备优异生物学功能与成药性的先到抗体,从而大幅提高抗体药物发现的效率。</p>\n<p>基于这一自有专利平台,天演药物现开发了三个核心产品:ADG106、ADG116和ADG126。其中用于治疗晚期实体瘤、非霍奇金淋巴瘤或NHL的ADG106正在中美两国进行临床试验,已被数据观察到具有良好的抗肿瘤活性与耐受性,最有望实现商业化。</p>\n<p>天演药业的另一产品ADG126,旨在解决与现有批准的CTLA-4免疫肿瘤疗法的MOA相关的毒性和功效问题,并扩大CTLA-4作为癌症治疗靶标的潜力。该产品现已由FDA获批,将于今年在美开展Ⅰ期临床试验。</p>\n<p>作为生物抗体领域的新星企业的创始人,天演药业创始人罗培志在医药科技领域颇为成功。罗培志毕业于北京大学,在美国芝加哥大学获得博士学位。2000年,罗培志创立了一家名为Abmaxis的生物医药公司,开创了不依赖抗体抗原的三维实验结构,可以设计和优化抗体的计算及筛选方法,为全球多家生物公司的创新药开发提供技术服务。因其技术创新,Abmaxis在2006年被默沙东收购,罗培志本人也受聘到默沙东担任全球生物制药研发主任。</p>\n<p>2011年左右,罗培志在校友、药明康德创始人李革的影响下,决定回国创业,很快将公司落户在离与药明康德总部无锡不远的苏州。2014年,天演药业完成A轮融资,共募集资金800万美元。领投机构包括药康明德创投基金、富达(波士顿)生物科技基金等。2016年天演药业的B轮融资,药明康德继续跟投,帮助天演药业再度融资2800万美元。此后的两年中,天演药业陆续完成了C轮、D轮融资,背后都有药明康德的身影。</p>\n<p>截至目前,药明康德仍以全资子公司无锡市医药科技保险基金的身份持有天演药业10.8%的股份。</p>\n<p>在国内CRO赛道上,药明康德无疑是领跑者。从2012年起,药明康德就开始布局投资具有潜力的Biotech公司,前期投资入股,获取未来收益。药明康德本身便具有一定的临床试验服务和生物分析等能力,在资金之外,其也可以凭借这些服务为初创公司提供支持。比如天演药业,在2018年至2020年两年里,共向药明康德购买了近1500万美元的研发服务与质量检测服务。</p>\n<p>财报显示,2018年、2019年及截至2020年9月30日的前9个月,由于产品均未上市,公司收入完全来自向制药公司新基授权专利所得,分别为151.1万美元、48万美元及31万美元。同一时期,研发支出在逐年上升,分别为1608.1万美元、1621.2万美元和2356.8万美元。</p>\n<p>没有能产生大额收入的上市药物,持续不断的研发投入也造成天演药业同期净亏损分别为1430.3万美元、1667.8万美元、2981.5万美元,归属于普通股股东的基本和摊薄每股亏损分别为0.94美元、1.10美元和1.89美元。</p>\n<p>目前,天演药业也在加大科研上的投入。公司在招股书中介绍,天演药业打算利用此次发行的净收益95%用于推进候选药物的试验,其中约26%的资金用于ADG106第一阶段试验和第二阶段试验的进展;26%的资金用于ADG126和ADG116;43%用于公司的技术和平台开发以及临床前候选药物的开发;剩余约5%用于营运资金和其他一般公司用途。</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/b19a2d6f03716b3591e388e25f762874","relate_stocks":{"ADAG":"天演药业"},"is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1194244001","content_text":"2月9日,临床阶段生物药企天演药业正式在纳斯达克挂牌上市,开盘涨8.95%,报20.7美元,市值8.73亿美元。\n\n天演药业发行价为19美元位于价格指导区间顶端,据悉本次发行735.4万份ADS,市值达到8.01亿美元。高盛、摩根士丹利、Jeffery为联席主承销商,华兴资本为副承销商。\n根据媒体报道,天演药业与CRO巨头药明康德的关系密切,药明康德系天演药业投资方之一,股份占比10.8%。有分析称,天演药业赴美上市,幕后助力者正是药明康德。\n根据官方信息,天演药业成立于2011年,致力于改变基于抗体的新型癌症免疫疗法的发现和开发。成立后的几年间,天演药业自主开发了动态精准抗体技术,建立起全球最大的多样性动态精准抗体库(DPL Platform),以及全球首个融合了精准计算设计与实验构造并集酵母和噬菌体于一体的高通量筛选平台。\n多样性动态精准抗体库是天演药业的核心技术专利。该DPL平台由计算物理技术与AI和大数据相结合提供支持,可对由海量抗体氨基酸序列产生的潜在无限数量的动态结合界面结构进行采样,生产同时具备优异生物学功能与成药性的先到抗体,从而大幅提高抗体药物发现的效率。\n基于这一自有专利平台,天演药物现开发了三个核心产品:ADG106、ADG116和ADG126。其中用于治疗晚期实体瘤、非霍奇金淋巴瘤或NHL的ADG106正在中美两国进行临床试验,已被数据观察到具有良好的抗肿瘤活性与耐受性,最有望实现商业化。\n天演药业的另一产品ADG126,旨在解决与现有批准的CTLA-4免疫肿瘤疗法的MOA相关的毒性和功效问题,并扩大CTLA-4作为癌症治疗靶标的潜力。该产品现已由FDA获批,将于今年在美开展Ⅰ期临床试验。\n作为生物抗体领域的新星企业的创始人,天演药业创始人罗培志在医药科技领域颇为成功。罗培志毕业于北京大学,在美国芝加哥大学获得博士学位。2000年,罗培志创立了一家名为Abmaxis的生物医药公司,开创了不依赖抗体抗原的三维实验结构,可以设计和优化抗体的计算及筛选方法,为全球多家生物公司的创新药开发提供技术服务。因其技术创新,Abmaxis在2006年被默沙东收购,罗培志本人也受聘到默沙东担任全球生物制药研发主任。\n2011年左右,罗培志在校友、药明康德创始人李革的影响下,决定回国创业,很快将公司落户在离与药明康德总部无锡不远的苏州。2014年,天演药业完成A轮融资,共募集资金800万美元。领投机构包括药康明德创投基金、富达(波士顿)生物科技基金等。2016年天演药业的B轮融资,药明康德继续跟投,帮助天演药业再度融资2800万美元。此后的两年中,天演药业陆续完成了C轮、D轮融资,背后都有药明康德的身影。\n截至目前,药明康德仍以全资子公司无锡市医药科技保险基金的身份持有天演药业10.8%的股份。\n在国内CRO赛道上,药明康德无疑是领跑者。从2012年起,药明康德就开始布局投资具有潜力的Biotech公司,前期投资入股,获取未来收益。药明康德本身便具有一定的临床试验服务和生物分析等能力,在资金之外,其也可以凭借这些服务为初创公司提供支持。比如天演药业,在2018年至2020年两年里,共向药明康德购买了近1500万美元的研发服务与质量检测服务。\n财报显示,2018年、2019年及截至2020年9月30日的前9个月,由于产品均未上市,公司收入完全来自向制药公司新基授权专利所得,分别为151.1万美元、48万美元及31万美元。同一时期,研发支出在逐年上升,分别为1608.1万美元、1621.2万美元和2356.8万美元。\n没有能产生大额收入的上市药物,持续不断的研发投入也造成天演药业同期净亏损分别为1430.3万美元、1667.8万美元、2981.5万美元,归属于普通股股东的基本和摊薄每股亏损分别为0.94美元、1.10美元和1.89美元。\n目前,天演药业也在加大科研上的投入。公司在招股书中介绍,天演药业打算利用此次发行的净收益95%用于推进候选药物的试验,其中约26%的资金用于ADG106第一阶段试验和第二阶段试验的进展;26%的资金用于ADG126和ADG116;43%用于公司的技术和平台开发以及临床前候选药物的开发;剩余约5%用于营运资金和其他一般公司用途。","news_type":1},"isVote":1,"tweetType":1,"viewCount":68,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":389552807,"gmtCreate":1612790940909,"gmtModify":1704874223547,"author":{"id":"3565838986169374","authorId":"3565838986169374","name":"手持一堆垃圾","avatar":"https://static.tigerbbs.com/70876ea3d18ea743551d4975c629d41a","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3565838986169374","authorIdStr":"3565838986169374"},"themes":[],"htmlText":".mn","listText":".mn","text":".mn","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/389552807","repostId":"1181758367","repostType":4,"repost":{"id":"1181758367","kind":"news","weMediaInfo":{"introduction":"为用户提供金融资讯、行情、数据,旨在帮助投资者理解世界,做投资决策。","home_visible":1,"media_name":"老虎资讯综合","id":"102","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1612790230,"share":"https://ttm.financial/m/news/1181758367?lang=&edition=fundamental","pubTime":"2021-02-08 21:17","market":"us","language":"zh","title":"比特币市值升至全球市值资产第8位,超越脸书","url":"https://stock-news.laohu8.com/highlight/detail?id=1181758367","media":"老虎资讯综合","summary":"2月8日,AssetDash数据显示,目前比特币市值超过7900亿美元,与知名公司股票市值相比,排名升至第8位,超越脸书(市值现报7651.57亿美元),排在特斯拉之后(市值现报8078.29亿美元)","content":"<p>2月8日,AssetDash数据显示,目前比特币市值超过7900亿美元,与知名公司股票市值相比,排名升至第8位,超越脸书(市值现报7651.57亿美元),排在<a href=\"https://laohu8.com/S/TSLA\">特斯拉</a>之后(市值现报8078.29亿美元)。</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>比特币市值升至全球市值资产第8位,超越脸书</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n比特币市值升至全球市值资产第8位,超越脸书\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time\">2021-02-08 21:17</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>2月8日,AssetDash数据显示,目前比特币市值超过7900亿美元,与知名公司股票市值相比,排名升至第8位,超越脸书(市值现报7651.57亿美元),排在<a href=\"https://laohu8.com/S/TSLA\">特斯拉</a>之后(市值现报8078.29亿美元)。</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/e8e7a6266784418dec934d26eb8ce628","relate_stocks":{},"is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1181758367","content_text":"2月8日,AssetDash数据显示,目前比特币市值超过7900亿美元,与知名公司股票市值相比,排名升至第8位,超越脸书(市值现报7651.57亿美元),排在特斯拉之后(市值现报8078.29亿美元)。","news_type":1},"isVote":1,"tweetType":1,"viewCount":309,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"lives":[]}