Prior to French biotech firm Abivax (ABVX.US) releasing data on its core drug obefazimod, investment bank Guggenheim raised the company's target stock price from $150 to $175 and assigned a "Buy" rating. Analyst Yatin Suneja stated that this adjustment is based on optimistic prospects for the upcoming 44th-week maintenance period data readout of its core drug obefazimod. On December 15, Abivax announced its Q3 2025 financial results. The company reported revenue of $2.4 million, exceeding market expectations by $1.06 million. However, the quarterly net loss per share totaled $1.68. The company's net loss for the first nine months widened to €254.1 million, up from €136.9 million in the same period of 2024. The company's financial activities reflect an increased focus on its lead drug candidate, obefazimod, a first-in-class oral miR-124 enhancer. Research and development expenses rose to €133.4 million, primarily driven by advancements in the ABTECT Phase III program for ulcerative colitis and the ENHANCE-CD Phase IIb trial for Crohn's disease. Abivax is gearing up for several key milestones in 2026. The primary results of the ABTECT maintenance trial are expected to be announced in Q2 2026, which will provide the final clinical basis for the planned New Drug Application (NDA) submission to the U.S. FDA in the second half of 2026.

