* Benchmark 10-year Treasury yields regain ground after auction
* Consumer prices up 8.5% in March vs est 8.4%
* Indexes down: Dow 0.26%, S&P 0.34%, Nasdaq 0.30%
NEW YORK, April 12 (Reuters) - Wall Street turned rally to sell-off on Tuesday, reversing earlier gains as impending monetary tightening from the Federal Reserve once again pulled growth stocks back into red territory.
All three major U.S. stock indexes turned from positive to negative early in the afternoon, weighed down by healthcare and financials.
The turnabout began in earnest shortly after remarks from Fed Governor Lael Brainard, who reiterated the need for the central bank to "expeditiously" take on decades-high inflation.
"The comments coming out from Fed officials have been more hawkish than the markets have anticipated," said Paul Nolte, portfolio manager at Kingsview Asset Management in Chicago. "(Brainard) has generally been nondescript, but now she’s more forceful in her commentary, and that’s getting people to sit up and take notice."
The Labor Department's CPI report showed the prices urban American consumers pay for a basket of goods posted the biggest monthly jump since September 2005, and an annual surge of 8.5%, the hottest year-on-year inflation number in more than four decades.
Much of the topline CPI growth was attributable to an 18.3% monthly surge in gasoline prices, to a record high of $4.33 per gallon.
The report did little to budge the needle of expectations regarding impending interest rate hikes from the Federal Reserve.
"It's reiteration the Fed can't be sitting back here," Nolte added. "They need to get moving, post-haste."
Early session gains were also dampened after a poor $34 billion 10-year Treasury auction, which helped benchmark yields bounce off session lows.
The Dow Jones Industrial Average fell 87.72 points, or 0.26%, to 34,220.36, the S&P 500 lost 15.08 points, or 0.34%, to 4,397.45 and the Nasdaq Composite dropped 40.38 points, or 0.3%, to 13,371.57.
Energy shares enjoyed the largest percentage gain among the 11 major sectors in the S&P 500, jumping 1.7% on the back of surging crude prices.
First-quarter earnings season bursts through the starting gate later this week, with big banks leading the way.
Analysts have curbed their first-quarter optimism. Annual S&P 500 earnings growth was recently estimated to be 6.1%, down from 7.5% at the beginning of the year.
CrowdStrike Holdings Inc rose 3.2% after Goldman Sachs upgraded the cybersecurity company's shares to "buy", citing elevated demand.
Declining issues outnumbered advancing ones on the NYSE by a 1.07-to-1 ratio; on Nasdaq, a 1.26-to-1 ratio favored decliners.
The S&P 500 posted 24 new 52-week highs and 15 new lows; the Nasdaq Composite recorded 53 new highs and 246 new lows.
Volume on U.S. exchanges was 11.25 billion shares, compared with the 12.60 billion average over the last 20 trading days.