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Alumis envudeucitinib hits 68% PASI 90 at Week 24 in Phase 3 psoriasis trials

Reuters03-30

Alumis envudeucitinib hits 68% PASI 90 at Week 24 in Phase 3 psoriasis trials
  • Alumis disclosed new Phase 3 ONWARD1 and ONWARD2 data showing envudeucitinib, an oral TYK2 inhibitor, delivered high levels of skin clearance in moderate-to-severe plaque psoriasis.
  • Results were presented as a late-breaking oral session at 2026 American Academy of Dermatology Annual Meeting.
  • PASI 90 reached 59.9% and 53.1% at Week 16, rising to 68% and 62.1% at Week 24.
  • PASI 100 was 29.4% and 27.7% at Week 16, increasing to 41% and 39.5% at Week 24.
  • Alumis plans to submit a U.S. New Drug Application in second half of 2026.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alumis Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001104659-26-036386), on March 30, 2026, and is solely responsible for the information contained therein.

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