Top Calls on Wall Street: Tesla, Amazon, Alphabet, Netflix, Apple, Eli Lilly & More
Here are Wednesday’s biggest calls on Wall Street:Barclays upgrades Urban Outfitters to overweight from equal weightBarclays said sales growth is “accelerating” at Urban Outfitters.“On the back of $URBN(URBN)$’s across-the-board solid 1Q23, we upgrade shares to Overweight based on positive inflections in our sales-to-inventory risk and inventory productivity metrics combined with positive sales growth.”Jefferies upgrades Sherwin-Williams to buy from holdJefferies said it sees an attractive risk/reward for the painting company.“$SHW(SHW)$’s risk/reward appears more balanced, particularly on a relative basis.”Bank of America adds Arista Networks to the US1 listBank of America added the networking equipment c
IDEAYA Biosciences, Inc., a synthetic lethality-focused precision medicine oncology company, focuses on the discovery and development of targeted therapeutics for patient populations selected using molecular diagnostics. The company's lead product candidates include IDE397, a methionine adenosyltransferase 2a inhibitor that is in Phase II clinical trial for patients with solid tumors having methylthioadenosine phosphorylase gene deletions; and IDE196, a protein kinase C inhibitor that is in Phase I/II clinical trial for genetically defined cancers having GNAQ or GNA11 gene mutations. Its preclinical pipeline includes various synthetic lethality programs targeting PARG inhibitor in tumors for patients having tumors with a defined biomarker based on genetic mutations and/or molecular signatures; Pol Theta inhibitors in tumors with BRCA or other homologous recombination deficiency mutations; and WRN inhibitors in tumors with high microsatellite instability. The company has a research collaboration agreement with Cancer Research UK and the University of Manchester todevelop small molecule inhibitors of Poly (ADP-ribose) glycohydrolase; and a clinical trial collaboration and supply agreement with Pfizer Inc. for Phase II/III study in metastatic uveal melanoma, as well as a strategic partnership with GlaxoSmithKline plc. IDEAYA Biosciences, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.